In this review schwechheimer and kuehn describe recent developments in elucidating the mechanisms of biogenesis and cargo selection of the outer membrane vesicles omvs produced by gram negative . The bacterial outer membrane is physiologically shed as the bounding membrane of outer membrane vesicles in cultures as well as in animal tissues at the host pathogen interface implicated in translocation of gram negative microbial biochemical signals to host or target cells biogenesis. Mi64ch09 kuehn ari 17 august 2010 1517 biological functions and biogenesis of secreted bacterial outer membrane vesicles adam kulp and meta j kuehn. Outer membrane protein biogenesis in gram negative bacteria rollauer se1 sooreshjani ma2 noinaj n3 buchanan sk4 author information 1national institute of diabetes and digestive and kidney diseases national institutes of health bethesda md 20892 usa. Biological functions and biogenesis of secreted bacterial outer membrane vesicles adam kulp and meta j kuehn called the inner and outer membranes the peptidoglycan layer and the periplasm the membranes differ in lipid and protein composition in most gram negative bacteria the outer leaflet of the outer membrane om is composed
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